Detalhe da pesquisa
1.
Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature
; 628(8009): 910-918, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38570680
2.
Nanoparticle-blockage-enabled rapid and reversible nanopore gating with tunable memory.
Proc Natl Acad Sci U S A
; 119(27): e2200845119, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35759673
3.
Molecular basis of multistep voltage activation in plant two-pore channel 1.
Proc Natl Acad Sci U S A
; 119(9)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210362
4.
Arachidonic acid reverses cholesterol and zinc inhibition of human voltage-gated proton channels.
J Biol Chem
; 299(7): 104918, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37315791
5.
Selective regulation of human TRAAK channels by biologically active phospholipids.
Nat Chem Biol
; 17(1): 89-95, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32989299
6.
Microsecond-timescale simulations suggest 5-HT-mediated preactivation of the 5-HT3A serotonin receptor.
Proc Natl Acad Sci U S A
; 117(1): 405-414, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31871207
7.
Molecular mechanism underlying modulation of TRPV1 heat activation by polyols.
J Biol Chem
; 297(1): 100806, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34022223
8.
CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions.
J Biol Chem
; 296: 100224, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33361160
9.
Gain-of-Function Mutations in KCNN3 Encoding the Small-Conductance Ca2+-Activated K+ Channel SK3 Cause Zimmermann-Laband Syndrome.
Am J Hum Genet
; 104(6): 1139-1157, 2019 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31155282
10.
A mutation in the S6 segment of the KvAP channel changes the secondary structure and alters ion channel activity in a lipid bilayer membrane.
Amino Acids
; 54(11): 1461-1475, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35896819
11.
Triplin: Functional Probing of Its Structure and the Dynamics of the Voltage-Gating Process.
Int J Mol Sci
; 23(22)2022 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430243
12.
Veratridine Can Bind to a Site at the Mouth of the Channel Pore at Human Cardiac Sodium Channel NaV1.5.
Int J Mol Sci
; 23(4)2022 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216338
13.
Mutations in KCNK4 that Affect Gating Cause a Recognizable Neurodevelopmental Syndrome.
Am J Hum Genet
; 103(4): 621-630, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30290154
14.
GJB1 mutations c.212T>G and c.311A>C induce apoptosis and inwardly rectifying potassium current changes in X-linked Charcot-Marie-Tooth type 1.
Biochem Biophys Res Commun
; 582: 8-15, 2021 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34678594
15.
Synthetic resin acid derivatives selectively open the hKV 7.2/7.3 channel and prevent epileptic seizures.
Epilepsia
; 62(7): 1744-1758, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34085706
16.
TRPM7-Mediated Calcium Transport in HAT-7 Ameloblasts.
Int J Mol Sci
; 22(8)2021 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33924361
17.
The Open State Selectivity of the Bean Seed VDAC Depends on Stigmasterol and Ion Concentration.
Int J Mol Sci
; 22(6)2021 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33809742
18.
Desensitization of NMDA channels requires ligand binding to both GluN1 and GluN2 subunits to constrict the pore beside the activation gate.
J Neurochem
; 153(5): 549-566, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31821563
19.
Cx32 hemichannel opening by cytosolic Ca2+ is inhibited by the R220X mutation that causes Charcot-Marie-Tooth disease.
Hum Mol Genet
; 27(1): 80-94, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29077882
20.
Structure and insights into the function of a Ca(2+)-activated Cl(-) channel.
Nature
; 516(7530): 213-8, 2014 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25337878